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Fibroblast orchestration of inflammaging via NF-kB activation (Aged vs Young Lung Fibroblasts and Epithelium)

ABSTRACT: In this study we used scRNA sequencing to compare lung fibroblast and epithelial populations from young and aged mice. We identified enrichment of a NF-kB activation signature in aged relative to young fibroblasts, particularly in the adventitial population.

ORGANISM(S): Mus musculus

PROVIDER: GSE286988 | GEO | 2025/12/04

REPOSITORIES: GEO

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