FeaSion Decodes the Regulatory Landscape and Functional Diversity of RNA Polymerase II CTD Phosphorylation

ABSTRACT: We utilize the FeaSion (Feature-Screening-Function) strategy to investigate five known phosphorylation states (pY1, pS2, pT4, pS5, pS7) of RNAPII. Our study demonstrates that mutations at these phosphorylation sites broadly influence transcriptional and co-transcriptional processes. And regulators of these sites involve various biological processes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE287316 | GEO | 2025/10/28

REPOSITORIES: GEO