Proteolytic cleavage of Tie1 governs vascular response to inflammatory stimulations

ABSTRACT: We here show that proteolytic cleavage of the Tie1 receptor evokes a vascular response to inflammatory stimulations such as TNFalpha and LPS. Resisting Tie1 cleavage reprogrammed EC gene networks, rendering them non-responsive to inflammatory stimulations.

ORGANISM(S): Mus musculus

PROVIDER: GSE287671 | GEO | 2026/07/24

REPOSITORIES: GEO