Early dissemination and prognostic value of circulating tumor cells in ductal carcinoma in situ

ABSTRACT: Widespread mammographic screening has resulted in a substantial increase in women diagnosed with Ductal Carcinoma in Situ (DCIS). To improve patient risk stratification, we investigate the prognostic value of circulating tumor cells (CTCs) as a biomarker for DCIS patients’ biological aggressiveness and as an indicator of early dissemination. Six enriched blood samples and six matching FFPE tissue samples are processed via single cell RNA sequencing.

ORGANISM(S): Homo sapiens

PROVIDER: GSE288451 | GEO | 2025/09/26

REPOSITORIES: GEO