A Novel EBF2 Nonsense Variant Drives Adipose Tissue Fibrosis and Dysfunction in Partial Lipodystrophy Syndrome

ABSTRACT: Heterozygous Ebf2 p.E165X knock-in (KI) mice exhibited restricted adipogenesis and excess extracellular matrix (ECM) deposition during post-weaning AT expansion and high-fat-diet (HFD)-induced obesity.

ORGANISM(S): Mus musculus

PROVIDER: GSE288829 | GEO | 2025/02/17

REPOSITORIES: GEO