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TGFβ maintains smooth muscle cell contractile phenotype via PDK4-dpendent regulation of Ac-CoA production [ATAC-Seq_TGF-siPDK4]

ABSTRACT: We find that TGFβ signaling in SMCs induced ACSS2-dependent production of Ac-CoA in a PDK4-dependent manner. TGFb induces SMC contractile phenotype and glycolysis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE288977 | GEO | 2025/09/01

REPOSITORIES: GEO

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Effect of TGFb on HASMC phenotype after 7 days of treatment

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TGFβ maintains smooth muscle cell contractile phenotype via PDK4-dpendent regulation of Ac-CoA production [ATAC-Seq_TGF-siPDK4]

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