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6K-plex RNA CosMx data from DLBCL sections.


ABSTRACT: Diffuse large B-cell lymphomas (DLBCLs) are a common and heterogeneous group of mature B-cell malignancies that typically arise in lymph nodes; sites in which stromal and endothelial cells, antigen-presenting cells and other myeloid cells facilitate adaptive immune responses by T-cells and B-cells against pathogens. In this study, we have leveraged the spatial transcriptomic platform of CosMx together with CODEX imaging technology to investigate the spatial immunology and pathobiology of DLBCL.

ORGANISM(S): Mus musculus Homo sapiens

PROVIDER: GSE289194 | GEO | 2025/05/26

REPOSITORIES: GEO

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