Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The alterations of gene expression profiling induced by ORM1 knockdown in HCT116 cells.

ABSTRACT: Recently, ORM1 was found to play an oncogenic role in in several cancers. Here we report gene expression profiles of HCT116 cells treated with ORM1 siRNA. This study reveals a novel role of ORM1 in downstream gene regulation and provides a new explanation of ORM1’ s function in colorectal cancer.

ORGANISM(S): Homo sapiens

PROVIDER: GSE289217 | GEO | 2026/02/09

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

The alterations of gene expression profiling induced by LINC00857 knockdown in HCT116 cells

Project description:Long noncoding RNAs (lncRNAs) have been identified to play increasingly important roles in tumorigenesis, and they may serve as novel biomarkers for cancer therapy. Recently, LINC00857 was found to play an oncogenic role in in several cancers. Here we report gene expression profiles of HCT116 cells treated with LINC00857 siRNA. This study reveals a novel role of LINC00857 in downstream gene regulation and provides a new explanation of LINC00857’ s function in colorectal cancer.

2022-08-15 | GSE201069 | GEO

The alterations of gene expression profiling induced by EXOSC10-AS1 knockdown in HCT116 cells.

Project description:Long noncoding RNAs (lncRNAs) have been identified to play increasingly important roles in tumorigenesis, and they may serve as novel biomarkers for cancer therapy. Here we report gene expression profiles of HCT116 cells treated with EXOSC10-AS1 siRNA. This study reveals a novel role of EXOSC10-AS1 in downstream gene regulation and provides a new explanation of EXOSC10-AS1’ s function in colorectal cancer.

2026-02-08 | GSE289213 | GEO

The alterations of gene expression profiling induced by ALKBH5 knockdown in HCT116 cells

Project description:ALKBH5 is one of the important m6A demethylases and is reported to be closely associated with tumorigenesis.In this study, we report gene expression profiles of HCT116 cells treated with ALKBH5 shRNA. This study reveals a novel role of ALKBH5 in downstream gene regulation and provides a new explanation ofALKBH5’ s function in colorectal cancer. Samples included 2 HCT1116 shNC and 2 HCT116 shALKBH5.

2024-09-30 | GSE213953 | GEO

Transcription changes due to TET1 knockdown in HCT116 colorectal cancer cells.

Project description:Transcriptional profiling of HCT116 cells transfected with either control siRNA or TET1 siRNA was analyzed using whole human genome microarrays. To identify genes regulated by TET1 in colorectal cancer, HCT116 cells were transfected with either control siRNA or TET1 siRNA, and total RNA was extracted from biologically duplicated samples.

2015-09-04 | E-GEOD-66512 | biostudies-arrayexpress

The alterations of gene expression profiling induced by ORM1 knockdown in HCT116 cells.

Project description:The alterations of gene expression profiling induced by ORM1 knockdown in HCT116 cells.

| PRJNA1221918 | ENA

BORIS knockdown in colorectal cancer cells HCT116 and Caco-2

Project description:BORIS expresses abnormally in colorectal cancer cells. Both the expression and the copy number of BORIS are remarkably higher in colorectal cancer cells than in normal colon or rectal cells. BORIS is potential diagnosis, prognosis or therapeutic target for colorectal cancer. To expand our view of the signaling pathway related with BORIS, altered gene expression by BORIS knockdown was assessed by microarray assay. To study the gene regulation by BORIS knockdown, microarray assay was applied to screen the gene expression regulated by BORIS siRNA in colorectal cancer cells HCT116 and Caco-2

2018-07-01 | GSE86172 | GEO

Knockdown of ADNP in HCT116 colon cancer cells

Project description:RNASeq data from replicates after siRNA mediated knockdown of human ADNP in HCT116 colon cancer cells

2016-11-23 | GSE79395 | GEO

Transcription changes due to TET1 knockdown in HCT116 colorectal cancer cells.

Project description:Transcriptional profiling of HCT116 cells transfected with either control siRNA or TET1 siRNA was analyzed using whole human genome microarrays.

2015-09-04 | GSE66512 | GEO

Effects of knockdown of ERK5 using PROTACs and siRNA on HCT116 cells

Project description:Changes in the cellular transcriptome, proteome and phosphorylated proteome after knockdown of ERK5 protein in HCT116 cells using PROTACs and siRNA, respectively.

2022-08-23 | PXD042635 |

Transcriptome profiling of HCT116 cells and HCT116 cells with knockdown of SETDB1 by RNA-sequencing

Project description:HCT116 is a colorectal cancer cell line. SETDB1 is an epigenetic modification factor responsible for catalyzing the histone modification H3K9me3. Transcription of SETDB1 gene is enriched in embryonic neural cells during vertebrate embryogenesis. SETDB1 is upregulated in cancer cells and promotes cancers. We found that knockdown of SETDB1 in HCT116 cells led to a neuronal-like differentiation phenotype.

2022-06-30 | GSE192372 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data