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Human TSLP administration promotes homeostatic maturation of human cDC2 in humanized mice

ABSTRACT: To test whether TSLP triggers homeostatic maturation of human cDC2s in vivo, we administrated human TSLP to humanized mice and performed scRNA-seq. We found that TSLP administration increased the proportion of homeostatically matured DC (DC2hm) subtype in cDCs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE289224 | GEO | 2026/02/23

REPOSITORIES: GEO

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TSLP administration promotes homeostatic maturation of human cDC2

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