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Human PSC-based Modeling of Pulmonary Fibrosis Identifies p300/CBP Inhibition as a Suppressor of Alveolar Transitional Cell State [epithelial]

ABSTRACT: In this study, we conducted a drug screening using an in vitro pulmonary fibrosis model and identified p300/CBP inhibitors as candidate therapeutic agents. We investigated the mechanisms underlying the emergence of the alveolar transitional cell state (ATCS) with human PSC-derived alveolar organoids.

ORGANISM(S): Homo sapiens

PROVIDER: GSE289676 | GEO | 2026/02/18

REPOSITORIES: GEO

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Human PSC-based Modeling of Pulmonary Fibrosis Identifies p300/CBP Inhibition as a Suppressor of Alveolar Transitional Cell State [BLM]

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