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Transcriptomics of salinomycin's molecular toxicity in turkey heart and liver

ABSTRACT: Salinomycin (Sal) is used as a coccidiostat to treat coccidiosis disease caused by Eimeria protozoa invasion in avian. Generally, salinomycin has been considered a safe feed additive if the recommended dosage is properly used depending on the animal species. However, in some cases, it has been reported that the accidental use, misuse, or interaction of salinomycin with other drugs generates toxicity in the organism. Yet, the exact molecular mechanisms of salinomycin intoxication have not been fully understood. To understand the salinomycin toxicity mechanism at the cellular level in turkey species we performed high-throughput sequencing using heart and liver samples.

ORGANISM(S): Meleagris gallopavo

PROVIDER: GSE289895 | GEO | 2025/07/09

REPOSITORIES: GEO

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