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Escape from X inactivation is directly modulated by Xist non-coding RNA [Astrocytes]

ABSTRACT: X-chromosome inactivation (XCI) silences one copy of the X-chromosome in female cells, but a number of genes escapes XCI. We asked whether increased levels of Xist RNA, the molecular actor driving X-inactivation, impacts expression levels of escapees in Astrocytes. To this end, we performed RNA-seq analysis profiling of X-linked genes upon doxycycline-induced Xist upregulation and following doxycycline washout.

ORGANISM(S): Mus

PROVIDER: GSE289898 | GEO | 2025/12/09

REPOSITORIES: GEO

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