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Escape from X inactivation is directly modulated by Xist non-coding RNA [E8.5]

ABSTRACT: X-chromosome inactivation silences one copy of the X-chromosome in female cells, but a number of genes escapes XCI. We asked whether increased levels of Xist RNA, the molecular actor driving X-inactivation, impacts expression levels of escapees. We tested whether dox-mediated Xist-overexpression affected the expression levels of escapees in extra-embryonic tissues.

ORGANISM(S): Mus

PROVIDER: GSE289900 | GEO | 2025/12/09

REPOSITORIES: GEO

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