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Profiling immune cells in the mammary gland during pregnancy and lactation

ABSTRACT: The mammary gland undergoes profound structural and cellular changes during pregnancy and lactation, yet the changes in immunocyte populations are incompletely understood. We identified changes in all immunocyte populations including B cells, NK cells, myeloid cells, and T cells, specifically increases in CD4+ and CD8+ T effector cells in late pregnancy and lactation that are partly dependent on microbial signals.

ORGANISM(S): Mus musculus

PROVIDER: GSE290256 | GEO | 2025/04/14

REPOSITORIES: GEO

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