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Interferon signaling underlies radiotherapy responses in malignant peripheral nerve sheath tumors (MPNSTs)

ABSTRACT: The clinical significance of specific genetic alterations, methylation signatures or microenvironmental composition in malignant peripheral nerve sheath tumors (MPNSTs) is unclear. We assembled an updated cohort of 30 patients with MPNSTs treated with surgical resection and postoperative radiation who underwent methylation profiling and detailed clinical follow-up. The data included in this submission include 7 of 30 samples, the remainder of which were submitted separately under GSE212963.

ORGANISM(S): Homo sapiens

PROVIDER: GSE290457 | GEO | 2025/11/22

REPOSITORIES: GEO

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