Cardiomyocyte OTUD1 drives diabetic cardiomyopathy via directly deubiquitinating AMPKα2 to inhibit AMPK activity and induce mitochondrial dysfunction

ABSTRACT: To analyze the mRNA profile of DUBs in diabetic heart, we performed a scRNA-seq of heart cells from the wild type (WT) mice and db/db mice, a typical T2DM model mouse.

ORGANISM(S): Mus musculus

PROVIDER: GSE290932 | GEO | 2025/06/11

REPOSITORIES: GEO