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Early life MES exposure inhibits testosterone production by upregulating TGF-β1 expression in mesenchymal cells by direct binding to GATA2

ABSTRACT: In this study, we investigated the effects of early life exposure to C18-MES on the reproductive system of mice, and by measuring semen quality, testicular structure, blood-testicular barrier integrity, and sex hormone levels, we clarified the reproductive toxicity of C18-MES and revealed its specific molecular regulatory mechanism.

ORGANISM(S): Mus musculus

PROVIDER: GSE291391 | GEO | 2025/10/01

REPOSITORIES: GEO

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Early life MES exposure inhibits testosterone production by upregulating TGF-β1 expression in mesenchymal cells by direct binding to GATA2

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