Establishment of Human Trophoblast Stem Cells from Term Smooth Chorion

ABSTRACT: Human trophoblast stem (TS) cells, which were established from blastocysts and first-trimester placental villi, can differentiate into the all trophoblastic subtypes, extravillous trophoblast (EVT) cells and syncytiotrophoblast (ST) cells. We newly generated human TS cells from the term smooth chorion (Ch-TS cells). They has the potential to differentiate into both ST and EVT cells as same as human TS cells derived from early placental villi. The transcriptomic profile of Ch-TS cells is also similar to conventional human TS cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE292125 | GEO | 2025/07/31

REPOSITORIES: GEO