Transcriptomics

Dataset Information

0

HybriSeq: Probe-based Device-free Single-cell RNA Profiling


ABSTRACT: We have developed the HybriSeq method for single-cell RNA profiling, which utilizes in situ hybridization of multiple probes for targeted transcripts, followed by split-pool barcoding and sequencing analysis of the probes. We have shown that HybriSeq can achieve high sensitivity for RNA detection with multiple probes and profile entire transcripts without an end bias. The utility of HybriSeq is demonstrated in characterizing cell-to-cell heterogeneities of a panel of 196 genes in peripheral blood mononuclear cells and the detection of missed annotations of transcripts.

ORGANISM(S): Mus musculus Homo sapiens

PROVIDER: GSE292322 | GEO | 2025/08/02

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2021-05-18 | GSE174541 | GEO
2009-10-27 | GSE15832 | GEO
2009-10-26 | E-GEOD-15832 | biostudies-arrayexpress
2010-10-15 | GSE24626 | GEO
2010-10-15 | GSE24699 | GEO
2024-02-14 | GSE245032 | GEO
2012-06-30 | GSE33021 | GEO
2012-06-29 | E-GEOD-33021 | biostudies-arrayexpress
2011-11-14 | E-GEOD-28018 | biostudies-arrayexpress
2011-03-01 | E-GEOD-14398 | biostudies-arrayexpress