RNA seq of activated CD8 T cells of WT and Card11 mutant mice(E134G/K215M)

ABSTRACT: To investigate the impact of Card11 on TCR downstream signaling, we isolated naive CD8+ T cells from wild-type (WT) mice and Card11 mutant mice (K215M and E134G). These cells were stimulated in vitro with anti-CD3/CD28 for 24 hours, after which RNA was extracted from the stimulated cells for sequencing analysis.

ORGANISM(S): Mus musculus

PROVIDER: GSE292542 | GEO | 2025/04/23

REPOSITORIES: GEO