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Bulk RNA-seq of PD1+/- T cels from mouse hearts 7 days post MI

ABSTRACT: Programmed cell death protein 1 (PD1) is crucial for adaptive immunity regulation, showing considerable effects in various diseases especially in tumor field. In order to deeply investigate the expression characteristics of PD1+ T cells in heart during myocardial infarction (MI), we firstly performed single-cell RNA sequencing (scRNA-seq) to characterize non-cardiomyocytes from mouse after MI. To further determine the activation of PD1+ T cells in MI, we sorted and sequenced PD1+ T cells accompanied with PD1- T cells in the mice heart after MI. In order to deeply investigate the function of PD1+ T cells in heart during MI, we performed single-cell RNA sequencing (scRNA-seq) to detect the change T cells from anti-IgG and anti-PD1 mouse after MI.

ORGANISM(S): Mus musculus

PROVIDER: GSE292863 | GEO | 2026/03/31

REPOSITORIES: GEO

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Single-cell RNA Sequencing of T Cells from ‌Anti-IgG and ‌Anti-PD1 injection Mouse hearts after MI

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