Effect of endoglin loss on embryoid bodies

ABSTRACT: Analysis of embryonic sten cell-derived embryoid bodies following endoglin knock out. Loss of endoglin leads to profound reduction of key hematopoietic regulators including SCL, LMO2, Gata2, and TGF-β signaling molecule ALK-1. Results provide insight into molecular mechanisms underlying hemangioblast and primitive hematopoietic development.

ORGANISM(S): Mus musculus

PROVIDER: GSE29300 | GEO | 2011/05/16

SECONDARY ACCESSION(S): PRJNA138629

REPOSITORIES: GEO