Transcriptional remodeling by OTX2 directs specification and patterning of mammalian definitive endoderm.
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ABSTRACT: We discovered a role for the transcription factor OTX2 in formation of mouse definitive endoderm (DE). We used RNAseq to measure changes in gene expression and identify OTX2-regulated genes during directed differentiation of EpiSCs to Primitive Streak (PS) intermediates and DE
ORGANISM(S): Mus musculus
PROVIDER: GSE293151 | GEO | 2025/07/21
REPOSITORIES: GEO
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