Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

TWIST1 drives endothelial-to-mesenchymal-transition to stabilize atherosclerotic plaques [Twist1 RNA-Seq]

ABSTRACT: The effect of TWIST1 deletion was studied in human aortic endothelial cells exposed to atheroprone or atheroprotective wall shear stress.

ORGANISM(S): Homo sapiens

PROVIDER: GSE293410 | GEO | 2026/01/12

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

TWIST1 drives endothelial-to-mesenchymal-transition to stabilize atherosclerotic plaques [AEBP1 RNA-Seq]

Project description:The effect of AEBP1 and PELP1 deletion was studied in human aortic endothelial cells exposed to atheroprone WSS, using the orbital system.

2026-01-12 | GSE293411 | GEO

TWIST1 drives endothelial-to-mesenchymal-transition to stabilize atherosclerotic plaques [single cell RNA-seq]

Project description:Single cell RNA sequencing (scRNA-seq) was used to analyse the diversity of ECs in the atherosclerotic mouse aorta, as well as the effect of endothelial-specific Twist1 deletion on aortic endothelial cells in mice exposed to a high fat diet.

2026-01-12 | GSE278596 | GEO

TWIST1 drives endothelial-to-mesenchymal-transition to stabilize atherosclerotic plaques [Twist1 RNA-Seq]

Project description:TWIST1 drives endothelial-to-mesenchymal-transition to stabilize atherosclerotic plaques [Twist1 RNA-Seq]

| PRJNA1244382 | ENA

TWIST1 drives endothelial-to-mesenchymal-transition to stabilize atherosclerotic plaques

Project description:TWIST1 drives endothelial-to-mesenchymal-transition to stabilize atherosclerotic plaques

| PRJNA1244375 | ENA

TWIST1 drives endothelial-to-mesenchymal-transition to stabilize atherosclerotic plaques

Project description:This SuperSeries is composed of the SubSeries listed below.

2026-01-12 | GSE293412 | GEO

TWIST1 drives endothelial-to-mesenchymal-transition to stabilize atherosclerotic plaques [AEBP1 RNA-Seq]

Project description:TWIST1 drives endothelial-to-mesenchymal-transition to stabilize atherosclerotic plaques [AEBP1 RNA-Seq]

| PRJNA1244383 | ENA

TWIST1 drives endothelial-to-mesenchymal-transition to stabilize atherosclerotic plaques [single cell RNA-seq]

Project description:TWIST1 drives endothelial-to-mesenchymal-transition to stabilize atherosclerotic plaques [single cell RNA-seq]

| PRJNA1168059 | ENA

Time series RNA profiling of endotheilal cells in response to atheroprone and atheroprotective flows

Project description:To profile shear stress-regulated endothelial transcriptomes, we performed RNA-seq with HUVECs subjected to different shear flow conditions, including atheroprotective pulsatile shear (PS, 12±4 dyn/cm2) and atheroprone oscillatory shear (OS, 0.5±4 dyn/cm2), or kept as static control (ST) for four time periods (1, 4, 12 and 24 hours)

2017-05-22 | GSE92506 | GEO

Transcriptional adaptations of HUVECs exposed to high and low fluid shear stress

Project description:The goal of this study was to identify gene signatures in HUVECs exposed to atheroprone low laminar shear stress (LSS) or atheroprotective high laminar shear stress (HSS). The obtained data was used to verify that HSS and LSS application induces gene expression patterns similar to more complex pulsatile and oscillatory flow, respectively.

2022-08-19 | GSE211662 | GEO

Histone Modifications and Chromatin Accessibility in Endothelial Cells under Shear Stress (ATAC-seq)

Project description:This data set reveals the changes of histone modifications and chromatin accessibility in human umbilical vein endothelial cells (HUVECs) under atheroprotective pulsatile shear (PS), atheroprone oscillatory shear (OS), or with KLF4 overexpression. Using ChIP-Seq, we defined the H3K27ac and H3K4me1 enrichment under PS and OS conditions. Using ATAC-seq, we identified the chromatin accessibility under KLF4 overexpression.

2020-03-11 | GSE128390 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data