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The foam cell-derived exosomes exacerbate ischemic white matter injury via transmitting metabolic defects to microglia

ABSTRACT: Experimental atherosclerosis was established by feeding Apoe KO mice a western diet(WD) for 14 weeks and experimental cerebral ischemia was established by bilateral carotid artery stenosis (BCAS). RNA-seq was perfomed to investigate the potential gene regulation of AS-Exos-dependent changes of microglia in the corpus callosum after BCAS.

ORGANISM(S): Mus musculus

PROVIDER: GSE293472 | GEO | 2025/04/30

REPOSITORIES: GEO

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