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Transcriptomic Profiling of TNFα-Stimulated Human Umbilical Vein Endothelial Cells (HUVECs) With and Without Isoginkgetin (ISOGK) Pretreatment.

ABSTRACT: We demonstrate that ISOGK attenuates endothelial inflammation through mechanistically distinct suppression of NF-κB p65 phosphorylation and nuclear translocation, highlighting its potential as a therapeutic agent for atherosclerosis intervention. This anti-inflammatory effect was associated with significant modulation of inflammatory pathway activation in vascular endothelial cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE293694 | GEO | 2025/05/15

REPOSITORIES: GEO

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Transcriptomic Profiling of TNFα-Stimulated Human Umbilical Vein Endothelial Cells (HUVECs) With and Without Isoginkgetin (ISOGK) Pretreatment.

Project description:Transcriptomic Profiling of TNFα-Stimulated Human Umbilical Vein Endothelial Cells (HUVECs) With and Without Isoginkgetin (ISOGK) Pretreatment.

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