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DNA-Diffusion STARR-Seq Validation

ABSTRACT: To test how DNA-Diffusion sequences can induce transcription, we select 2150 sequences, including DNA-Diffusion synthetic and natural occurring DHS sites for each cell type (K562, HepG2, and GM12878) and insert them into STARR-Seq plasmids (N= 6450 sequences). all synthetic and naturally occurring sequences were combined into a single library, and this same library was experimentally tested using STARR-Seq in different cell lines (K562, HepG2, GM12878).

ORGANISM(S): Homo sapiens

PROVIDER: GSE293971 | GEO | 2025/10/07

REPOSITORIES: GEO

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