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β-Hydroxybutyrate Boosts Plant Immunity through Enhanced histone Kbhb Levels and Gene Expression Regulation [RNA-seq]

ABSTRACT: We demonstrated functional differences between H3K9bhb and the well-studied H3K9ac, particularly in regulating immune-response genes in rice. Moreover, we show that exogenous application of β-hydroxybutyrate enhances disease resistance in rice by inducing H3K9bhb deposition and stimulating the expression of defense-related genes. Furthermore, we identified SRT1, SRT2, and HDA705 as key players in the removal of histone Kbhb in rice plants.

ORGANISM(S): Oryza sativa Japonica Group

PROVIDER: GSE294824 | GEO | 2025/06/07

REPOSITORIES: GEO

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β-Hydroxybutyrate Boosts Plant Immunity through Enhanced histone Kbhb Levels and Gene Expression Regulation [ATAC-seq]

Project description:We demonstrated functional differences between H3K9bhb and the well-studied H3K9ac, particularly in regulating immune-response genes in rice. Moreover, we show that exogenous application of β-hydroxybutyrate enhances disease resistance in rice by inducing H3K9bhb deposition and stimulating the expression of defense-related genes. Furthermore, we identified SRT1, SRT2, and HDA705 as key players in the removal of histone Kbhb in rice plants.

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