MRNA sequencing on esophageal organoids derived from K5:Smo mice 5 days after tamoxifen injection.
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ABSTRACT: In our study, we used mRNA sequencing to investigate the effect of 3 days-treatment with a combination of TGFb1 and BMP with or without ibuprofen.
Project description:In our study, we used mRNA sequencing to investigate the effect of ibuprofen on the transcriptome of esophageal epithelial cells of K5:Smo mice.
Project description:In our study, we used single-cell RNA sequencing to investigate the effect of ibuprofen on cell-mediated communication between esophageal epithelial cells and their microenvironment in K5:Smo mice.
Project description:In our study, we used single-cell RNA sequencing to investigate the early effects of Hedgehog signaling pathway activation in esophageal progenitors.
Project description:In our study, we used mRNA sequencing to investigate the effect of 3 days-treatment with TGFb1, BMP4 alone or in combination on the squamous and columnar differentiation.
Project description:Single cell mRNA sequencing on esophageal cells of WT and Krt5-CreERT2:R26SmoM2/EYFP (K5:Smo) mice 5 days after Tamoxifen administration
Project description:We treated intestinal organoids continuously for 5 days with or without TgfbR1/2 inhibitor (LY2109761) or Tgfb1 ligand Organoids were continuously treated for 5 days, then RNA was extracted and hybridized to Affymetrix Mouse Genome 430 2.0