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Transcriptomic profiling of CD11b+ myeloid cells isolated from tumor-bearing mice treated with vehicle or TP-18.

ABSTRACT: To investigate the antitumor mechanisms of the dual EP2/EP4 antagonist TP-18, CD11b+ myeloid cells were isolated from CT26 tumors, with or without TP-18 treatment, and subjected to RNA-seq–based transcriptomic profiling.

ORGANISM(S): Mus musculus

PROVIDER: GSE295287 | GEO | 2025/05/06

REPOSITORIES: GEO

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Transcriptomic profiles of CT26 syngeneic tumor tissues following treatment with the dual EP2/EP4 antagonist TP-18.

Project description:To investigate the antitumor mechanisms of the dual EP2/EP4 antagonist TP-18, we conducted RNA-seq-based transcriptomic analysis of CT26 tumors, with or without TP-18 treatment.

2025-05-06 | GSE295286 | GEO

Transcriptomic profiles of CT26 syngeneic tumor tissues following treatment with the dual EP2/EP4 antagonist TP-18.

Project description:Transcriptomic profiles of CT26 syngeneic tumor tissues following treatment with the dual EP2/EP4 antagonist TP-18.

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Transcriptomic profiling of CD11b+ myeloid cells isolated from tumor-bearing mice treated with vehicle or TP-18.

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