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Single cell landscape of MBL/CLL transition [MBL_CLL_GEO_DataSet1]

ABSTRACT: The transition of monoclonal B cell lymphocytosis (MBL) to chronic lymphocytic leukemia (CLL) remains ill-defined at the epigenetic and transcriptional level. Here, we performed single cell RNA and ATAC sequencing of low-count (LC) and high-count (HC) MBL and CLL blood samples to track the continuum from physiologic B cells to CLL.

ORGANISM(S): Homo sapiens

PROVIDER: GSE295489 | GEO | 2026/03/31

REPOSITORIES: GEO

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Single cell landscape of MBL/CLL transition [MBL_CLL_GEO_DataSet3]

Project description:The transition of monoclonal B cell lymphocytosis (MBL) to chronic lymphocytic leukemia (CLL) remains ill-defined at the epigenetic and transcriptional level. Here, we performed single cell RNA and ATAC sequencing of low-count (LC) and high-count (HC) MBL and CLL blood samples to track the continuum from physiologic B cells to CLL.

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