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DNA methylation analysis in MCF-7 cell line with overexpression of POU1F1

ABSTRACT: The transcription factor POU1F1 plays an important role in breast cancer. It has been described that POU1F1 is capable of regulating the expression of different genes involved in cell proliferation, apoptosis and cell plasticity. The mechanism by which POU1F1 carries out these regulations is still unknown, and epigenetics is one of the possible causes. Epigenetics refers to modifications in gene expression that are heritable through cell division and that occur without changes in the DNA sequence. DNA methylation is one of the most important epigenetic mechanisms.

ORGANISM(S): Homo sapiens

PROVIDER: GSE295731 | GEO | 2025/05/06

REPOSITORIES: GEO

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Study of epithelial-mesenchymal transition induced by POU1F1 in normal breast cells

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ChIP-chip from pregnant female mouse pituitary with POU1F1 (PIT-1)

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Control of the anterior pituitary cell lineage regulator POU1F1 by the stem cell determinant Musashi

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Reprogramming breast cancer cells to breast cancer stem cells-like by the POU1F1 transcription factor

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Modification of genes expression in the somatolactotrope GH4C1 cell line in presence of the dominant negative mutant POU1F1(R271W)

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ChIP-chip from pregnant female mouse pituitary with POU1F1 (PIT-1)

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DNA methylation analysis in MCF-7 cell line with overexpression of POU1F1

Project description:DNA methylation analysis in MCF-7 cell line with overexpression of POU1F1

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| ENSRNOG00000000715 | ExpressionAtlas

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