Bulk B Cell Receptor Sequencing of mouse ileum; paired sample with MERFISH imaging

ABSTRACT: Plasma B cell clones each express a single B cell receptor that has high binding specificity to a narrow set of antigens. New spatial technologies have been introduced that aim to capture the clonality of plasma cell populations in situ. BCR-MERFISH is an imaging- and probe-based spatial approach that targets the V genes of heavy and light chains that comprise B cell receptors within single cells. To assess how accurately BCR-MERFISH reports V gene usage, this BCR-sequencing dataset was collected from paired samples that were imaged with BCR-MERFISH.

ORGANISM(S): Mus musculus

PROVIDER: GSE295989 | GEO | 2026/08/18

REPOSITORIES: GEO