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Genome-wide identification of transcriptional targets for H3K18la in adipose stem and progenitor cells

ABSTRACT: In this study, we found that H3K18la level is elevated in adipose stem and progenitor cells of facial infiltrating lipomatosis (FIL-ASPCs). To further explore the potential functional significance of H3K18la in FIL, we performed genome-wide cleavage under targets and tagmentation (CUT&Tag) analysis to identify candidate genes regulated by H3K18la in FIL-ASPCs and CON-ASPCs. Following CUT&Tag, H3K18la-associated DNAs were amplified using non-biased conditions, labeled, and sequenced with Illumina NovaSeq 150PE.

ORGANISM(S): Homo sapiens

PROVIDER: GSE296002 | GEO | 2025/08/25

REPOSITORIES: GEO

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