Methylation profiling

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Developmental Programming: Differing impact of prenatal testosterone and prenatal bisphenol-A -treatment on hepatic methylome in female sheep


ABSTRACT: Steroid hormones play a crucial role in pregnancy and fetal development, influencing metabolism, inflammation, and immune responses. Excessive prenatal exposure to steroids or environmental chemicals like bisphenol A can disrupt offspring's metabolism. This study examines how prenatal exposure to testosterone and BPA affects the liver's DNA methylome, which is critical for long-term health.

ORGANISM(S): Ovis aries

PROVIDER: GSE296249 | GEO | 2025/08/22

REPOSITORIES: GEO

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