Widespread non-Mendelian inheritance of DNA methylation patterns in mice [ONT Muscle]

ABSTRACT: We performed long-read ONT sequencing on two Collaborative Cross mouse strains and their F1 crosses. Allele-specific methylation analyses revealed widespread and diverse patterns of intergenerational epigenetic inheritance. Included among these are a large number of non-Mendelian inheritance patterns, many of which have not previously been observed in naturally occurring mammalian genomes.

ORGANISM(S): Mus musculus

PROVIDER: GSE296494 | GEO | 2026/03/16

REPOSITORIES: GEO