Tomatidine Attenuates Inflammatory Responses to Exercise-Like Stimulation in Donor-derived Skeletal Muscle Myobundles

ABSTRACT: We assessed donor-specific response to tomatidine known to inhibit muscle atrophy and promote skeletal muscle hypertrophy. Bioinformatic analyses revealed that infusion of tomatidine during electrical stimulation modulated the IL-6/JAK/STAT3 pathway improving muscle synchronicity in young myobundles compared to those from older volunteers.

ORGANISM(S): Homo sapiens

PROVIDER: GSE296683 | GEO | 2025/08/27

REPOSITORIES: GEO