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S100A8/A9-related myocardial injury after non-cardiac surgery: RNA sequencing analysis in a novel mouse model

ABSTRACT: The aim of this study was to develop a new mouse model of myocardial injury after non-cardiac surgery (MINS) and to elucidate its pathophysiology. Male C57BL/6 mice underwent abdominal surgery under sevoflurane anesthesia, and myocardial samples were collected at multiple time points post-surgery. Gene expression profiling using RNA sequencing data from these samples was performed to investigate the molecular changes associated with MINS.

ORGANISM(S): Mus musculus

PROVIDER: GSE296854 | GEO | 2025/05/17

REPOSITORIES: GEO

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