Differentiation of tumor-infiltrating GZMK+ effector memory T cells associates with response to neoadjuvant immunotherapy in head and neck cancer

ABSTRACT: We performed single-cell RNA/VDJ-sequencing of sorted T cells from pre- and post-treatment tumor biopsies of patients with HPV-unrelated head and neck squamous cell carcinoma treated with either bintrafusp alfa alone or in combination with Tri-Ad5 vaccine.

ORGANISM(S): Homo sapiens

PROVIDER: GSE296954 | GEO | 2026/06/15

REPOSITORIES: GEO