UVDE-HS-seq map of 6-4PP and atypical TA photoproducts in UV-irradiated normal human skin fibroblasts and UV-irradiated genomic DNA

ABSTRACT: UV-induced pyrimidine-pyrimidone (6-4) photoproducts (6-4PPs) and atypical thymine-adenine (TA) photoproducts were mapped in normal human skin fibroblasts following 500J/m2 of UVC irradiation and in isolated human genomic DNA (naked DNA control) irradiated with 400J/m2 of UVC irradiation. 6-4PPs and TA-PPs were mapped across the human genome using the UVDE-HS-seq method

ORGANISM(S): Homo sapiens

PROVIDER: GSE297236 | GEO | 2026/02/10

REPOSITORIES: GEO