Transcriptomics

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RNA sequence for RMG1 cells with HIF2A knockdown under 1.5% O₂ for 24 hours


ABSTRACT: We performed RNA-seq analysis on ovarian clear cell carcinoma (OCCC) cell lines to investigate the transcriptional effects of HIF2A knockdown. Hypoxia-inducible factor 2 alpha (HIF2A) plays a key role in cellular adaptation to low oxygen environments and has been implicated in tumor progression. In this study.A human OCCC cell line, RMG1, was cultured under hypoxic conditions following lentiviral transduction with shHIF2A or a control vector. This dataset provides insights into the downstream gene expression changes and mitochondrial function modulated by HIF2A suppression.

ORGANISM(S): Homo sapiens

PROVIDER: GSE297968 | GEO | 2025/12/15

REPOSITORIES: GEO

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