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RNA-seq analysis of MLO-Y4 cells under hypoxic conditions

ABSTRACT: To investigate the effects of hypoxia on osteocytes, we cultured MLO-Y4 osteocytic cells under normoxic (20% O₂) and hypoxic (2% O₂) conditions. We then performed gene expression profiling analysis using RNA-seq data obtained from these cells. Differential expression analysis revealed that Lipocalin 2 (LCN2) was one of the most significantly upregulated genes under hypoxic conditions.The dataset provides insights into the transcriptional response of osteocytes to hypoxic stress.

ORGANISM(S): Mus musculus

PROVIDER: GSE298138 | GEO | 2025/05/30

REPOSITORIES: GEO

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