Transcriptomic Profiling of Escherichia coli and Salmonella enterica Reveals Regulatory Roles of the 3′ UTR-Derived sRNA UhpU Under Various Growth Conditions

ABSTRACT: To investigate the biological function and regulatory impact of the 3′ UTR-derived small RNA (sRNA) UhpU, we performed transcriptomic analyses in both Escherichia coli and Salmonella enterica under multiple growth conditions. These include short-term pulse expression of UhpU in minimal medium supplemented with glucose-6-phosphate (G6P) or LB medium, as well as a comparative transcriptomic analysis of wild-type and ΔuhpTU deletion strains during LB growth. This dataset provides insight into UhpU’s regulatory roles in metabolic adaptation and its evolutionary diversification across species.

ORGANISM(S): Escherichia coli Salmonella enterica subsp. enterica

PROVIDER: GSE298437 | GEO | 2025/11/17

REPOSITORIES: GEO