Maternal gut microbial legacy shapes intestinal health and colitis susceptibility of offspring

ABSTRACT: Offspring born to mothers with colitis exhibited gut microbial dysbiosis, impaired barrier function, low-grade intestinal inflammation, compromised Wnt signaling and reduced crypt cell proliferation, which collectively increased their susceptibility to colitis in adulthood.

ORGANISM(S): Mus musculus

PROVIDER: GSE298759 | GEO | 2026/02/18

REPOSITORIES: GEO