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Effect of FL-Fc-DM1 drug on gene expression of THP-1 cells

ABSTRACT: To eliminate cell-cycle arrested AML cells, we developed a FL-Fc-DM1 drug by conjugating FLT3 liangd Fc fusion protein and mertansine. We used the THP-1 cells as a AML model. The total mRNA of THP-1 cells treated with different concentration of FL-Fc-DM1 were sequenced.

ORGANISM(S): Homo sapiens

PROVIDER: GSE300849 | GEO | 2025/06/30

REPOSITORIES: GEO

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