Immune dynamics in allergic mice small intestines after allergen-encapsulating nanoparticle therapy

ABSTRACT: Polymeric allergen-loaded nanoparticles were used as a treatment for a murine model of food allergies. To study the immune changes due to allergic disease and nanoparticle treatment, single-cell RNA sequencing of the small intestine lamina propria was done at various timepoints. This study investigates immune dynamics in allergic and allergic nanoparticle-treated mice before and after OFC-induced anaphylaxis.

ORGANISM(S): Mus musculus

PROVIDER: GSE300948 | GEO | 2026/05/23

REPOSITORIES: GEO