TRNA gene identity acts as a determinant of gene positioning

ABSTRACT: Here we report that the spatial organization of yeast tRNA genes depends upon both locus position and tRNA identity; supporting the idea that the genomic organization of tRNA loci utilizes tRNA dependent signals within the nucleoprotein-tRNA complexes that form into clusters. We use high-throughput sequencing coupled to Circular Chromosome Conformation Capture to detect interactions with two wild type tRNAs and these same positions replaced with suppressor tRNAs (SUP4-1).

ORGANISM(S): Saccharomyces cerevisiae

PROVIDER: GSE30103 | GEO | 2012/06/14

SECONDARY ACCESSION(S): PRJNA143893

REPOSITORIES: GEO