A global transcriptome analysis of human dermal fibroblasts upon knockdown of the circular RNAs CircMT-RNR2

ABSTRACT: In an RNAseq analysis, we have identified CircMT-RNR2 with lower levels in diabetic foot ulcer compared to healthy skin The biological function of CircMT-RNR2 in human dermal fibroblasts during wound repair has not been studied. To study the genes regulated by CircMT-RNR2, we transfected siRNA into human dermal fibroblasts to knockdown CircMT-RNR2. We performed a global transcriptome analysis of fibroblasts upon circRNA knockdown using Affymetrix arrays.

ORGANISM(S): Homo sapiens

PROVIDER: GSE301636 | GEO | 2026/05/20

REPOSITORIES: GEO