Transcriptomics

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Bulk RNAseq of in vitro human Rett syndrome neurons with addition of NAD supplementation


ABSTRACT: Here we employed RNA-seq on neuronal cultures differentiated from human induced pluripotent stem cells (hIPSCs) derived from Rett syndrome patients. The study aims to understand the effects of PARP stimulation through the treatment of nicotinamide adenine dinucleotide (NAD) on gene expression of MECP2 mutant neurons.

ORGANISM(S): Homo sapiens

PROVIDER: GSE301702 | GEO | 2025/07/15

REPOSITORIES: GEO

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