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Circulating Epigenetic Signatures Classifying Brain Insulin Resistance in humans [1]

ABSTRACT: Brain insulin action plays an important role in metabolic and cognitive health but so far, there is no biomarker available to assess brain insulin resistance in humans. Here, we developed a machine learning framework based on blood DNA methylation profiles of participants who did not have Type 2 Diabetes with and without brain insulin resistance and detailed metabolic phenotyping.

ORGANISM(S): Homo sapiens

PROVIDER: GSE301735 | GEO | 2026/04/08

REPOSITORIES: GEO

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Circulating Epigenetic Signatures Classifying Brain Insulin Resistance in humans [2]

Project description:Brain insulin action plays an important role in metabolic and cognitive health but so far, there is no biomarker available to assess brain insulin resistance in humans. Here, we developed a machine learning framework based on blood DNA methylation profiles of participants who did not have Type 2 Diabetes with and without brain insulin resistance and detailed metabolic phenotyping.

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Circulating Epigenetic Signatures Classifying Brain Insulin Resistance in humans

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Circulating Epigenetic Signatures Classifying Brain Insulin Resistance in humans

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